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Among the most important functions of glial cells are to support neurons and hold them in place; to supply nutrients to neurons; to insulate neurons electrically; to destroy pathogens and remove dead neurons; and to provide guidance cues directing the axons of neurons to their targets.

A very important type of glial cell (oligodendrocytes in the central nervous system, and Schwann cells in the peripheral nervous system) generates layers of a fatty substance called myelin that wraps around axons and provides electrical insulation which allows them to transmit action potentials much more rapidly and efficiently.

In the insect nervous system, the brain is anatomically divided into the protocerebrum, deutocerebrum, and tritocerebrum.

Immediately behind the brain is the subesophageal ganglion, which is composed of three pairs of fused ganglia.

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